Early variations of laboratory parameters predicting shunt-dependent hydrocephalus after subarachnoid hemorrhage

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Early variations of laboratory parameters predicting shunt-dependent hydrocephalus after subarachnoid hemorrhage

BACKGROUND AND PURPOSE Hydrocephalus is a frequent complication following subarachnoid hemorrhage. Few studies investigated the association between laboratory parameters and shunt-dependent hydrocephalus. This study aimed to investigate the variations of laboratory parameters after subarachnoid hemorrhage. We also attempted to identify predictive laboratory parameters for shunt-dependent hydroc...

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Cerebrospinal fluid tenascin-C increases preceding the development of chronic shunt-dependent hydrocephalus after subarachnoid hemorrhage.

BACKGROUND AND PURPOSE The possible cause of chronic hydrocephalus after subarachnoid hemorrhage (SAH) has been reported to be meningeal fibrosis. We examined whether the induction of tenascin-C (TN-C), an extracellular matrix glycoprotein known to promote tissue fibrosis, was associated with chronic hydrocephalus after SAH. METHODS We prospectively measured cerebrospinal fluid TN-C levels in...

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Shunt-Dependent Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage: Predictors and Long-Term Functional Outcomes.

BACKGROUND Although chronic hydrocephalus requiring shunt placement is a known sequela of aneurysmal subarachnoid hemorrhage (aSAH), its effect on long-term functional outcomes is incompletely understood. OBJECTIVE To identify predictors of shunt-dependent hydrocephalus and shunt complications after aSAH and determine the effect of shunt dependence on functional outcomes in aSAH patients. M...

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Acute hydrocephalus after subarachnoid hemorrhage.

This issue of Stroke includes an important discussion of acute hydrocephalus after subarachnoid hemorrhage (SAH), contributed by a group of investigators from The Netherlands who have made several important recent contributions to our understanding of the pathophysiology of SAH. The data of Hasan et al, derived from a careful study of 473 consecutive patients with SAH admitted within 72 hours a...

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Chronic Hydrocephalus after Experimental Subarachnoid Hemorrhage

Chronic communicating hydrocephalus is a significant health problem affecting up to 20% of survivors of spontaneous subarachnoid hemorrhage (SAH). The development of new treatment strategies is hampered by the lack of well characterized disease models. This study investigated the incidence of chronic hydrocephalus by evaluating the temporal profile of intracranial pressure (ICP) elevation after...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2017

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0189499